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Clinical data
Trade namesLioresal, Liofen, Gablofen, others
License dataUS   FDA: Baclofen
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth, intrathecal
ATC codeM03BX01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) US: ℞-only
Pharmacokinetic data
Protein binding30%
Metabolism85% excreted in urine/faeces unchanged. 15% metabolised by deamination
Elimination half-life1.5 to 4 hours
ExcretionRenal (70–80%)

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The Cochrane Database of Systematic Reviews. doi.Therefore, patients at risk of overdose including those with history of self-harm, over-dose, current suicidal ideation, or repeated and recent suicidal attempts should not be prescribed baclofen.

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