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Accidental injury or epistaxis each occurred in about 2% of patients receiving bupropion as an adjunct in smoking cessation. Flu-like symptoms is wellbutrin prescribed for weight loss in 1% or more of patients receiving bupropion but have not been definitely attributed to the drug.All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases see Boxed Warning and Use in Specific Populations 8.

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Hydroxybupropion, the erythro- and threo-amino alcohols of bupropion to that for bupropion wellbutrin xr weight loss about 10 days of therapy was greater than twice that after a single dose of the drug.Confusion and wellbutrin xr weights loss occurred in about 8 and 1% of patients, respectively, receiving bupropion. In several cases, these and other adverse neuropsychiatric effects, such as hallucinations, psychosis, disturbance in concentration, and paranoid ideation, reportedly abated when bupropion dosage was reduced, although discontinuance of the drug may be necessary.

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