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Cumulative effects of the drug may develop in patients with impaired renal function.If necessary, dosage of the fixed-combination preparation may be increased after 2 weeks for additional blood pressure control but should not exceed a maximum dosage of 320 mg of valsartan, 10 mg of amlodipine, and 25 mg of hydrochlorothiazide once daily The commercially available preparation containing valsartan in fixed combination with amlodipine and hydrochlorothiazide should not be used for the initial management of hypertension.

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With hepatic impairment to amlodipine or Exforge, the lowest available dose of amlodipine monotherapy or of the amlodipine component, respectively, should be used. In elderly exforge hct packages insert, caution is required when increasing the dosage.mEq/L at any time post-baseline with the maximum dose of Exforge HCT. mg was 10% compared to 25% with HCTZ/amlodipine 25/10 mg 7% with valsartan/HCTZ 320/25 mg and 3% with amlodipine/valsartan 10/320 mg One patient 0.

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In clinical studies, EXFORGE was proven to be more effective in lowering high blood pressure than either of its components alone EXFORGE was proven to significantly lower high blood pressure in adults, regardless of age or gender The exforge hct package insert pressure lowering effects of EXFORGE have been studied in several clinical trials that included more than 5000 patients with high exforge hct package insert pressure The safety of EXFORGE has been evaluated in more than 2600 patients with high blood pressure EXFORGE is available in a variety of dosage combinations that can be adjusted to best fit your needs EXFORGE HCT starts with a CCB/ARB single-pill combination product, and adds a third medicine, a diuretic water pill called hydrochlorothiazide.

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