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Shepherd J, Cobbe SM, Vapor I, et al, for the Personally of Asia Coronary Fibrosis Study Group WOS Fibrin of lipitor and low platelet count heart muscle with pravastatin in men with hypercholesterolemia. The Wherever-term Possible with Pravastatin in Ischemic Skepticism Splitter LIPID Squatting of cardiovascular events and cramping with pravastatin in men with countless heart condition and a broad disparity of worn cholesterol levels.

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The use of fibrates alone is occasionally associated with myopathy.Pravastatin is used together with diet to lower blood levels of "bad" Cholesterol low-density lipoprotein, or LDL to increase levels of "good" Cholesterol high-density lipoprotein, or HDL and to lipitor and low platelet count triglycerides a type of fat in the blood Pravastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with or without coronary heart disease or other risk factors.

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Years median of 5. years and at randomization had Total-C lipitor and low platelet count 114 and 563 mg/dL mean 219 mg/dL LDL-C between 46 and 274 mg/dL mean 150 mg/dL TG between 35 and 2710 mg/dL mean 160 mg/dL and HDL-C between 1 and 103 mg/dL mean 37 mg/dL At baseline, 82% of patients were receiving aspirin and 76% were receiving antihypertensive medication.The range of composite scores is 20-80.

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And also. Data from controlled studies indicate that safety and tolerability of pravastatin at a dosage of 80 mg pravastatin and low platelet count is similar to those at lower dosages.The drug should be discontinued immediately if pregnancy is known or suspected.

Women of childbearing potential should use effective contraception while receiving the drug.

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Therefore effects of simvastatin on abnormal lipid metabolism were compared with those of pravastatin when each drug was administered alone at an initial dose in patients with hypercholesterolemia by a crossover atorvastatin and platelet count. During the observation period, patients were confirmed to be appropriate subjects for the study, and after their consent was obtained, they were randomly divided into the following two groups by using an envelope method: group S-P for 8-week treatment with simvastatin 5 mg followed by 8-week treatment with pravastatin 10 mg and atorvastatin and platelet count P-S for 8-week treatment with pravastatin 10 mg followed by 8-week treatment with simvastatin 5 mg Each drug was administered once a day after the evening meal.of atorvastatin and platelets count randomized to receive usual care were receiving antilipemic therapy 26.

with a statin Despite the reported lack of clinical benefit, the study results are consistent with previous findings indicating that lesser degrees of cholesterol lowering are associated with less clinical benefit.

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Eople taking this medicine during childhood or adolescence may need a different dose as adults.Cholesterol and other products of cholesterol biosynthesis are essential components for pravastatin and low platelet count development including synthesis of steroids and cell membranes Since statins decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol, they are contraindicated during pregnancy and in nursing mothers.

PRAVASTATIN SHOULD BE ADMINISTERED TO WOMEN OF CHILDBEARING AGE ONLY WHEN SUCH PATIENTS ARE HIGHLY UNLIKELY TO CONCEIVE AND HAVE BEEN INFORMED OF THE POTENTIAL HAZARDS.

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Ng/mL and 59. ng*hr/mL, respectively.N Engl J Med. 2004 Apr. 1495-504.

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This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.ardiosource. rg or y.

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Pravastatin is contraindicated in cans atorvastatin cause low platelet count who may become pregnant.rg Pravastatin is used as an adjunct to nondrug therapies i. lifestyle modifications in patients with hypercholesterolemia without clinical evidence of coronary heart disease CHD to reduce the risk of myocardial infarction MI to reduce the risk of undergoing myocardial revascularization procedures, and to reduce the risk of cardiovascular mortality with no increase in death from noncardiovascular causes The ACC/AHA cholesterol management guideline recommends statins as first-line therapy for primary prevention in patients 21 years of age and older without clinical ASCVD who have primary, severe elevations in LDL-cholesterol concentration 190 mg/dL or greater patients 40-75 years of age with type 1 or 2 diabetes mellitus; and patients 40-75 years of age with LDL-cholesterol concentrations of 70-189 mg/dL and an estimated 10-year ASCVD risk of 7.

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Aspirin and pravastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Avoid drinking alcohol while taking aspirin and pravastatin.There was no clinically lipitor and low platelet count decrease in bioavailability or therapeutic effect when pravastatin was administered one hour before or four hours after colestyramine or one hour before colestipol see section 4.

Ciclosporin: concomitant administration of pravastatin and ciclosporin leads to an approximately 4-fold increase in pravastatin systemic exposure.

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